Connecting the dots: Why knowledge graphs matter

BioStrand (a subsidiary of IPA)
3 min readSep 14, 2023

Knowledge Graphs (KGs) have become a must-know innovation that will drive transformational benefits in data-centric AI applications across industries. KGs, big data and AI are complementary concepts that together address the challenges of integrating, unifying, analyzing and querying vast volumes of diverse and complex data.

There are several inherent advantages to the KG approach to organizing and representing information. Unlike traditional flat data structures, for instance, a KG framework is designed to model multilevel hierarchical, associative, and causal relationships that more accurately represent real-world data. The application of a semantic layer to data also makes it easier for both humans and machines to understand the context and significance of information.

Here then are some of the key features and benefits of knowledge graphs.

Efficient Data Integration:

Integrate disparate data sources and break down information silos

AI-specific data management, including automated data and metadata integration, is a critical component in successful data-centric AI . However, factors such as data complexity, quality, and accessibility pose integration challenges that are barriers to AI adoption . Data-centric AI requires a modern approach to data integration that integrates all organizational data entities into one unified semantic representation based on context (ontologies, metadata, domain knowledge, etc.) and time (temporal relationships).

There are several advantages to KG data models. They have the flexibility to scale across complex heterogeneous data structures. When integrated with natural language technologies (NLT), KGs can help train language models on domain-specific knowledge and natural language technologies can streamline the construction of knowledge models. They allow for more intuitive querying of complex data even by users without specialized data science knowledge. They can to assimilate new data, sources, definitions, and use cases without manageability and accessibility loss . They provide consistent and unified access to all organization knowledge that is typically distributed across different data silos and systems.

Rich Contextualization:

Capture relationships and provide a holistic view of data

KGs leverage the powers of context and relations to embed data with intelligence. By organizing data based on factual interconnections and interrelations, they add real-world meaning to data that makes it easier for AI systems to extract knowledge from vast volumes of data.

With KGs, smart behavior is encoded directly into the data so that the graph itself can dynamically understand connections and associations between entities, eliminating the need to manually program every new piece of information.

Knowledge graphs provide context for decision support and can be further classified based on use cases as actioning KGs (data management) and decisioning KGs (analytics), and as context-rich KGs (internal knowledge management), external-sensing KGs (external data mapping), and natural language processing KGs.

Enhanced Search and Discovery:

Enable precise and context-aware search results

The first step towards understanding how KGs transform the data search and discovery function is to understand the distinction between data search and data discovery.

Data search broadly refers to a scenario in which users are looking for specific information that they know or assume to exist. This is a framework that allows users to seek and extract relevant information from volumes of non-relevant data. Data discovery is focused more on proactively enabling users to surface and explore new information and ideas that are potentially related to the actual search string. Discovery essentially is search powered by context.

KGs contextually integrate all entities and relationships across different data silos and systems into a unified semantic layer. This enables them to more accurate and comprehensive search results and to provide context-relevant connections and relationships that promote knowledge discovery. Users can then follow the contextual links that are most pertinent to their interest to delve deeper into the data thereby boosting data utilization and value. And perhaps equally importantly, the intuitive and flexible querying capabilities of KGs allow even non-technical users to explore data and discover new insights.

Knowledge graphs in life sciences

Knowledge graphs are transformative frameworks that enable a structured, connected, and semantically-enhanced approach to organize and interpret data holistically. They provide the foundations for companies to create a uniform data fabric across different environments and technologies and operationalizing AI at scale.

Originally published at on September 14, 2023.



BioStrand (a subsidiary of IPA)

Software and proprietary solutions for MULTI-omics data analysis. Effective research requires convenient and scalable tools.